MCM3 anticorps (N-Term)

N° du produit ABIN6263161

Détail du produit anti-MCM3 anticorps

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: MCM3 Antibody detects endogenous levels of total MCM3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCM3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MCM3

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Autre désignation: MCM3 (MCM3 Produits)

Synonymes: anticorps HCC5, anticorps P1-MCM3, anticorps P1.h, anticorps RLFB, anticorps AL033361, anticorps C80350, anticorps Mcmd, anticorps P1, anticorps p1.m, anticorps cb32, anticorps chunp6867, anticorps wu:fa26g03, anticorps CG4206, anticorps DmMCM3, anticorps DmMcm3, anticorps DmeMCM3, anticorps Dmel\\CG4206, anticorps MCM3, anticorps McM3, anticorps Mcp-PCR2, anticorps PCR2, anticorps dMCM3, anticorps xmcm3, anticorps minichromosome maintenance complex component 3, anticorps MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), anticorps Minichromosome maintenance 3, anticorps minichromosome maintenance complex component 3 L homeolog, anticorps MCM complex subunit Mcm3, anticorps MCM3, anticorps mcm3, anticorps Mcm3, anticorps mcm3.L

Sujet:

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Gene: MCM3

Poids moléculaire: 91kDa

ID gène: 4172

UniProt: P25205

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA