MCM5 anticorps (N-Term)

N° du produit ABIN6263163

Détail du produit anti-MCM5 anticorps

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MCM5 Antibody detects endogenous levels of total MCM5.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCM5, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl,sodium azide and glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5 (MCM5 Produits)

Synonymes: anticorps 23.m06024, anticorps cdc46, anticorps xmcm5, anticorps CDC46, anticorps P1-CDC46, anticorps Afu5g02520, anticorps NCU01171.1, anticorps AA617332, anticorps AI324988, anticorps AL033333, anticorps Cdc46, anticorps Mcmd5, anticorps mCD46, anticorps mCDC46, anticorps mcm5, anticorps wu:fb34a06, anticorps CG4082, anticorps DmCDC46, anticorps DmCDC465, anticorps DmMCM5, anticorps DmMcm5, anticorps DmeMCM5, anticorps Dmel\\CG4082, anticorps MCM5, anticorps McM5, anticorps PCR4, anticorps DNA replication licensing factor MCM5, anticorps minichromosome maintenance complex component 5 S homeolog, anticorps minichromosome maintenance complex component 5, anticorps DNA replication licensing factor Mcm5, anticorps DNA replication licensing factor mcm5, anticorps MCM5 minichromosome maintenance deficient 5 (S. cerevisiae), anticorps minichromosome maintenance complex component 5 L homeolog, anticorps Minichromosome maintenance 5, anticorps DNA replication licensing factor mcm-5, anticorps BBOV_IV010040, anticorps mcm5.S, anticorps MCM5, anticorps AFUA_5G02520, anticorps NCU01171, anticorps PVX_084615, anticorps LOC5576119, anticorps CpipJ_CPIJ008678, anticorps Bm1_24480, anticorps CMU_022890, anticorps Mcm5, anticorps mcm5, anticorps TP01_0722, anticorps mcm5.L, anticorps mcm-5

Sujet:

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

Gene: MCM5

Poids moléculaire: 90kDa

ID gène: 4174

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA