MCM6 anticorps (C-Term)

N° du produit ABIN6263166

Détail du produit anti-MCM6 anticorps

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: MCM6 Antibody detects endogenous levels of total MCM6.

Homologie: Pig,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCM6, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MCM6

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Autre désignation: MCM6 (MCM6 Produits)

Synonymes: anticorps CG4039, anticorps DmMCM6, anticorps DmeMCM6, anticorps Dmel\\CG4039, anticorps MCM6, anticorps McM6, anticorps fs(1)K1214, anticorps mcm6, anticorps MCG40308, anticorps Mis5, anticorps P105MCM, anticorps Mcmd6, anticorps mis5, anticorps mmcm6, anticorps ASP-l1, anticorps D1Wsu22e, anticorps Minichromosome maintenance 6, anticorps DNA replication licensing factor MCM6, anticorps minichromosome maintenance complex component 6, anticorps minichromosome maintenance complex component 6 L homeolog, anticorps DNA replication licensing factor mcm-6, anticorps Mcm6, anticorps TP02_0113, anticorps PVX_114735, anticorps CMU_027970, anticorps MCM6, anticorps mcm6.L, anticorps mcm-6

Sujet:

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Gene: MCM6

Poids moléculaire: 93kDa

ID gène: 4175

UniProt: Q14566

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA