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MECP2 anticorps (C-Term)

MECP2 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263186
  • Antigène Voir toutes MECP2 Anticorps
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Épitope
    • 19
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 101
    • 39
    • 30
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 100
    • 7
    • 1
    Lapin
    Clonalité
    • 101
    • 7
    Polyclonal
    Conjugué
    • 62
    • 10
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MECP2 est non-conjugé
    Application
    • 79
    • 64
    • 35
    • 30
    • 12
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    MeCP2 Antibody detects endogenous levels of total MeCP2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MeCP2, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MECP2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Autre désignation
    MECP2 (MECP2 Produits)
    Synonymes
    anticorps AUTSX3, anticorps MRX16, anticorps MRX79, anticorps MRXS13, anticorps MRXSL, anticorps PPMX, anticorps RS, anticorps RTS, anticorps RTT, anticorps 1500041B07Rik, anticorps BB130002, anticorps D630021H01Rik, anticorps Mbd5, anticorps WBP10, anticorps wu:fk96a04, anticorps zgc:111857, anticorps methyl-CpG binding protein 2, anticorps methyl CpG binding protein 2, anticorps methyl-CpG binding protein 2 S homeolog, anticorps MECP2, anticorps Mecp2, anticorps mecp2, anticorps mecp2.S
    Sujet

    Description: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

    Gene: MECP2

    Poids moléculaire
    75 kDa
    ID gène
    4204
    UniProt
    P51608
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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