MEMO1 anticorps (N-Term)

N° du produit ABIN6263219

Détail du produit anti-MEMO1 anticorps

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEMO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: MEMO1 Antibody detects endogenous levels of total MEMO1.

Homologie: Pig,Zebrafish,Bovine,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MEMO1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MEMO1

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Autre désignation: MEMO1 (MEMO1 Produits)

Synonymes: anticorps MGC89105, anticorps C2orf4, anticorps MEMO, anticorps NS5ATP7, anticorps 0610016J10Rik, anticorps D930048L02Rik, anticorps RGD1309929, anticorps fi04d12, anticorps wu:fi04d12, anticorps zgc:55290, anticorps mediator of cell motility 1, anticorps mediator of cell motility 1 L homeolog, anticorps MEMO1, anticorps memo1, anticorps Memo1, anticorps memo1.L

Sujet:

Description: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Gene: MEMO1

Poids moléculaire: 33 kDa

ID gène: 51072

UniProt: Q9Y316