MESDC2 anticorps (Internal Region)

N° du produit ABIN6263227

Détail du produit anti-MESDC2 anticorps

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MESDC2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: MESDC2 Antibody detects endogenous levels of total MESDC2.

Homologie: Zebrafish,Bovine,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MESDC2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MESDC2

Antigène: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Autre désignation: MESDC2 (MESDC2 Produits)

Synonymes: anticorps MGC115616, anticorps MESDC2, anticorps BOCA, anticorps MESD, anticorps 2210015O11Rik, anticorps AW537813, anticorps mKIAA0081, anticorps mesd, anticorps msd, anticorps zgc:158636, anticorps mesoderm development LRP chaperone, anticorps mesoderm development LRP chaperone L homeolog, anticorps mesoderm development candidate 2, anticorps MESD, anticorps mesd.L, anticorps CpipJ_CPIJ010816, anticorps Tsp_04045, anticorps mesd, anticorps Mesd, anticorps MESDC2

Sujet:

Description: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).

Gene: MESDC2

Poids moléculaire: 26 kDa

ID gène: 23184

UniProt: Q14696