Lysine (K)-Specific Methyltransferase 2B (KMT2B) (Internal Region) anticorps

N° du produit ABIN6263280

Détail du produit

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: MLL2 Antibody detects endogenous levels of total MLL2.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MLL2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détail du antigène

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Autre désignation: KMT2D (KMT2B Produits)

Synonymes: anticorps HRX2, anticorps MLL1B, anticorps MLL2, anticorps MLL4, anticorps TRX2, anticorps WBP7, anticorps lysine methyltransferase 2B, anticorps KMT2B

Sujet:

Description: Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.

Gene: KMT2D

Poids moléculaire: 593kDa

ID gène: 8085

UniProt: O14686

Pathways: L'effet Warburg