MMP14 anticorps (C-Term)

N° du produit ABIN6263294

Détail du produit anti-MMP14 anticorps

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: MMP14 Antibody detects endogenous levels of total MMP14.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MMP14, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14 (MMP14 Produits)

Synonymes: anticorps MMP1, anticorps MMP-14, anticorps MMP-X1, anticorps MT-MMP, anticorps MT-MMP 1, anticorps MT1-MMP, anticorps MT1MMP, anticorps MTMMP1, anticorps mmp-x1, anticorps mt1-mmp, anticorps mtmmp1, anticorps AI325305, anticorps MT-MMP-1, anticorps sabe, anticorps Mt1-mmp, anticorps MT-MMPbeta, anticorps cb386, anticorps sb:cb386, anticorps wu:fb72b09, anticorps mmp14, anticorps matrix metallopeptidase 14, anticorps matrix metallopeptidase 14 (membrane-inserted), anticorps matrix metallopeptidase 14b (membrane-inserted), anticorps matrix metallopeptidase 14a (membrane-inserted), anticorps matrix metallopeptidase 14 L homeolog, anticorps MMP14, anticorps mmp14, anticorps Mmp14, anticorps mmp14b, anticorps mmp14a, anticorps mmp14.L

Sujet:

Description: Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).

Gene: MMP14

Poids moléculaire: 65kDa

ID gène: 4323

UniProt: P50281

Pathways: Autophagy