MTM1 anticorps (C-Term)
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- Antigène Voir toutes MTM1 Anticorps
- MTM1 (Myotubularin 1 (MTM1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTM1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- MTM1 Antibody detects endogenous levels of total MTM1.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human MTM1, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MTM1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- MTM1 (Myotubularin 1 (MTM1))
- Autre désignation
- MTM1 (MTM1 Produits)
- Synonymes
- anticorps CNM, anticorps MTMX, anticorps XLMTM, anticorps wu:fb19c01, anticorps zgc:123266, anticorps myotubularin 1, anticorps myotubularin 1 S homeolog, anticorps MTM1, anticorps mtm1, anticorps mtm1.S, anticorps Mtm1
- Sujet
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Description: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Gene: MTM1
- Poids moléculaire
- 70kDa
- ID gène
- 4534
- UniProt
- Q13496
- Pathways
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
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