Nicastrin anticorps (C-Term)
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- Antigène Voir toutes Nicastrin (NCSTN) Anticorps
- Nicastrin (NCSTN)
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Nicastrin est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- NCSTN Antibody detects endogenous levels of total NCSTN.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human NCSTN, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NCSTN Anticorps primaire
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anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 429-669) antibodyNCSTN Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 21-120) antibodyNCSTN Reactivité: Souris WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 99-133) antibodyNCSTN Reactivité: Humain, Rat WB Hôte: Lapin Polyclonal RB53031 unconjugated
anti-Nicastrin (NCSTN) (AA 1-689) antibodyNCSTN Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 16-115) antibodyNCSTN Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1E8 unconjugated
anti-Nicastrin (NCSTN) (AA 420-655) antibodyNCSTN Reactivité: Humain WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 35-534) antibodyNCSTN Reactivité: Rat WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 168-289) antibodyNCSTN Reactivité: Humain, Souris, Rat, Poulet, Chien WB, IF Hôte: Souris Monoclonal 35-Nicastrin unconjugated
anti-Nicastrin (NCSTN) (N-Term) antibodyNCSTN Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- Nicastrin (NCSTN)
- Autre désignation
- NCSTN (NCSTN Produits)
- Sujet
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Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Gene: NCSTN
- Poids moléculaire
- 77kDa
- ID gène
- 23385
- UniProt
- Q92542
- Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
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