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NDC80 anticorps (C-Term)

NDC80 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263548
  • Antigène Voir toutes NDC80 Anticorps
    NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
    Épitope
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 48
    • 20
    • 11
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 39
    • 9
    • 1
    Lapin
    Clonalité
    • 41
    • 8
    Polyclonal
    Conjugué
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp NDC80 est non-conjugé
    Application
    • 29
    • 19
    • 10
    • 10
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    NDC80 Antibody detects endogenous levels of total NDC80.
    Homologie
    Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human NDC80, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NDC80 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
    Autre désignation
    NDC80 (NDC80 Produits)
    Synonymes
    anticorps CG9938, anticorps Dmel\\CG9938, anticorps Hec1, anticorps NDC80, anticorps dNdc80, anticorps dmNdc80, anticorps hec1, anticorps KNTC2, anticorps ndc10, anticorps tid3, anticorps 2610020P18Rik, anticorps AV139730, anticorps HEC, anticorps HEC1, anticorps Kntc2, anticorps kntc2l, anticorps wu:fb52e02, anticorps zgc:111801, anticorps HsHec1, anticorps TID3, anticorps hsNDC80, anticorps kntc2, anticorps NDC80, kinetochore complex component, anticorps CG9938 gene product from transcript CG9938-RA, anticorps spindle pole body protein Ndc80, anticorps kinetochore protein Ndc80, anticorps NDC80 homolog, kinetochore complex component (S. cerevisiae), anticorps NDC80 kinetochore complex component, anticorps NDC80 kinetochore complex component S homeolog, anticorps NDC80, anticorps Ndc80, anticorps ndc80, anticorps ndc80.S
    Sujet

    Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).

    Gene: NDC80

    Poids moléculaire
    74kDa
    ID gène
    10403
    UniProt
    O14777
    Pathways
    Maintenance of Protein Location
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