NEURL anticorps (Internal Region)
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- Antigène Voir toutes NEURL Anticorps
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NEURL est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.
- Homologie
- Pig,Bovine,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NEURL Anticorps primaire
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anti-Neuralized Homolog (Drosophila) (NEURL) (AA 158-186) antibody
NEURL Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB21920 unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser357) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1248) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Internal Region) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Center) antibodyNEURL Reactivité: Humain WB, IHC, IF, IC Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser351) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1112) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser352) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
- Autre désignation
- NEURL1 (NEURL Produits)
- Sujet
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Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Gene: NEURL1
- Poids moléculaire
- 62kDa
- ID gène
- 9148
- UniProt
- O76050
- Pathways
- Signalisation Notch, EGFR Signaling Pathway
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