NKX3-1 anticorps (Internal Region)

N° du produit ABIN6263648

Détail du produit anti-NKX3-1 anticorps

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: NKX3.1 Antibody detects endogenous levels of total NKX3.1.

Homologie: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NKX3.1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3-1 (NKX3-1 Produits)

Synonymes: anticorps Xbagpipe, anticorps Xbap, anticorps bagpipe, anticorps koza, anticorps nkx3-1, anticorps nkx3.1, anticorps si:ch211-67o1.2, anticorps nkx3a, anticorps MGC53041, anticorps MGC97890, anticorps Bax, anticorps NKX3.1, anticorps NKX3A, anticorps Nkx-3.1, anticorps BAPX2, anticorps NKX3, anticorps NK3 homeobox 1 L homeolog, anticorps NK3 homeobox 1, anticorps NK-3 transcription factor, locus 1 (Drosophila), anticorps nkx3-1.L, anticorps NKX3-1, anticorps nkx3-1, anticorps Nkx3-1

Sujet:

Description: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Gene: NKX3-1

Poids moléculaire: 38kDa

ID gène: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus