Nth Endonuclease III-Like 1 (NTHL1) anticorps
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- Antigène Voir toutes Nth Endonuclease III-Like 1 (NTHL1) Anticorps
- Nth Endonuclease III-Like 1 (NTHL1)
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
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Application
- Western Blotting (WB), ELISA
- Specificité
- NTHL1 Antibody detects endogenous levels of total NTHL1
- Réactivité croisée
- Humain, Souris
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human NTHL1
- Isotype
- IgG
- Top Product
- Discover our top product NTHL1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- Nth Endonuclease III-Like 1 (NTHL1)
- Autre désignation
- NTHL1 (NTHL1 Produits)
- Synonymes
- anticorps psmc3, anticorps psmc3-a, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps nthl1.S
- Sujet
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Description: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
Gene: NTHL1
- Poids moléculaire
- 34 kDa
- ID gène
- 4913
- UniProt
- P78549
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