SLC22A6 anticorps (Internal Region)

N° du produit ABIN6263787

Détail du produit anti-SLC22A6 anticorps

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: SLC22A6 Antibody detects endogenous levels of total SLC22A6.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SLC22A6, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SLC22A6

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Autre désignation: SLC22A6 (SLC22A6 Produits)

Synonymes: anticorps HOAT1, anticorps OAT1, anticorps PAHT, anticorps ROAT1, anticorps NKT, anticorps Oat1, anticorps Orctl1, anticorps mOat1, anticorps slc22a6, anticorps zgc:77073, anticorps SLC22A6, anticorps Paht, anticorps Roat1, anticorps nkt, anticorps oat1, anticorps oat1-B, anticorps paht, anticorps roat1, anticorps slc22a6-B, anticorps Slc22a6, anticorps solute carrier family 22 member 6, anticorps solute carrier family 22 (organic anion transporter), member 6, anticorps solute carrier family 22 (organic anion transporter), member 6, like, anticorps Solute carrier family 22 member 6, anticorps solute carrier family 22 (organic anion transporter), member 6 S homeolog, anticorps SLC22A6, anticorps Slc22a6, anticorps slc22a6l, anticorps s22a6, anticorps slc22a6.S

Sujet:

Description: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

Gene: SLC22A6

Poids moléculaire: 61 kDa

ID gène: 9356

UniProt: Q4U2R8

Pathways: Dicarboxylic Acid Transport