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OBFC2A anticorps (Internal Region)

OBFC2A Reactivité: Humain WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263791
  • Antigène Voir toutes OBFC2A Anticorps
    OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
    Épitope
    • 5
    • 1
    • 1
    Internal Region
    Reactivité
    • 9
    • 2
    • 2
    Humain
    Hôte
    • 9
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 5
    • 2
    • 1
    • 1
    Cet anticorp OBFC2A est non-conjugé
    Application
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    OBFC2A Antibody detects endogenous levels of total OBFC2A.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human OBFC2A, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))
    Autre désignation
    NABP1 (OBFC2A Produits)
    Synonymes
    anticorps OBFC2A, anticorps SOSS-B2, anticorps SSB2, anticorps 4930434H03Rik, anticorps 4930442A21Rik, anticorps 4930488J04Rik, anticorps 4933440J18Rik, anticorps 5830411E10Rik, anticorps AI852561, anticorps Nbp1, anticorps Obfc2a, anticorps Ssb2, anticorps RGD1306658, anticorps nucleic acid binding protein 1, anticorps NABP1, anticorps Nabp1
    Sujet

    Description: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

    Gene: NABP1

    Poids moléculaire
    22 kDa
    ID gène
    64859
    UniProt
    Q96AH0
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