P4HTM anticorps (Internal Region)
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- Antigène Voir toutes P4HTM Anticorps
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp P4HTM est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- P4HTM Antibody detects endogenous levels of total P4HTM.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human P4HTM, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product P4HTM Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Autre désignation
- P4HTM (P4HTM Produits)
- Synonymes
- anticorps Ph-4, anticorps RGD1311848, anticorps EGLN4, anticorps HIFPH4, anticorps P4H-TM, anticorps PH-4, anticorps PH4, anticorps PHD4, anticorps 4933406E20Rik, anticorps AI853847, anticorps BB128974, anticorps prolyl 4-hydroxylase, transmembrane, anticorps prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum), anticorps shisa family member 5, anticorps P4htm, anticorps P4HTM, anticorps SHISA5
- Sujet
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Description: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Gene: P4HTM
- Poids moléculaire
- 57 kDa
- ID gène
- 54681
- UniProt
- Q9NXG6
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