PAM anticorps (Internal Region)

N° du produit ABIN6264025

Détail du produit anti-PAM anticorps

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: PAM Antibody detects endogenous levels of total PAM.

Homologie: Pig,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PAM, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PAM

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Autre désignation: PAM (PAM Produits)

Synonymes: anticorps PAL, anticorps PHM, anticorps pal, anticorps phm, anticorps pamb, anticorps CG3832, anticorps Dmel\\CG3832, anticorps dPHM, anticorps AE-I, anticorps PAL-A, anticorps PHM-A, anticorps pama, anticorps si:dkeyp-35f12.2, anticorps peptidylglycine alpha-amidating monooxygenase, anticorps peptidylglycine alpha-amidating monooxygenase S homeolog, anticorps Peptidylglycine-alpha-hydroxylating monooxygenase, anticorps peptidylglycine alpha-amidating monooxygenase L homeolog, anticorps PAM, anticorps Pam, anticorps pam.S, anticorps CHLREDRAFT_150435, anticorps sce7070, anticorps pam, anticorps Phm, anticorps pam.L

Sujet:

Description: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.

Gene: PAM

Poids moléculaire: 108 kDa

ID gène: 5066

UniProt: P19021