PASK anticorps (C-Term)

N° du produit ABIN6264045

Détail du produit anti-PASK anticorps

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PASK est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: PASK Antibody detects endogenous levels of total PASK.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PASK, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PASK

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Autre désignation: PASK (PASK Produits)

Synonymes: anticorps pas, anticorps wu:fb69h07, anticorps PASK, anticorps PASKIN, anticorps STK37, anticorps mKIAA0135, anticorps PAS domain containing serine/threonine kinase, anticorps Pask, anticorps pask, anticorps PASK

Sujet:

Description: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Gene: PASK

Poids moléculaire: 142kDa

ID gène: 23178

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process