KAT2B anticorps (C-Term)

N° du produit ABIN6264062

Détail du produit anti-KAT2B anticorps

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: PCAF Antibody detects endogenous levels of total PCAF.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PCAF, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur KAT2B

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Autre désignation: KAT2B (KAT2B Produits)

Synonymes: anticorps PCAF, anticorps pcaf, anticorps si:ch211-1j13.2, anticorps zgc:161980, anticorps gb:dq017634, anticorps im:7156024, anticorps CAF, anticorps P, anticorps P/CAF, anticorps A930006P13Rik, anticorps AI461839, anticorps AW536563, anticorps Pcaf, anticorps p/CAF, anticorps lysine acetyltransferase 2B, anticorps K(lysine) acetyltransferase 2B, anticorps K(lysine) acetyltransferase 2A, anticorps KAT2B, anticorps kat2b, anticorps kat2a, anticorps Kat2b

Sujet:

Description: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 (PubMed:27796307).

Gene: KAT2B

Poids moléculaire: 93kDa

ID gène: 8850

UniProt: Q92831

Pathways: Signalisation p53, Regulation of Carbohydrate Metabolic Process