PDZK1 anticorps (C-Term)

N° du produit ABIN6264124

Détail du produit anti-PDZK1 anticorps

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: PDZK1 Antibody detects endogenous levels of total PDZK1.

Homologie: Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PDZK1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZK1 (PDZK1 Produits)

Synonymes: anticorps xpdzk1, anticorps PDZK1, anticorps CAP70, anticorps CLAMP, anticorps NHERF-3, anticorps NHERF3, anticorps PDZD1, anticorps 1700023D20Rik, anticorps 2610507N21Rik, anticorps 4921513F16Rik, anticorps AI267131, anticorps AI314638, anticorps AL022680, anticorps D3Ertd537e, anticorps Pdzd1, anticorps mPDZK1, anticorps Clamp, anticorps PDZ domain containing 1, anticorps PDZ domain containing 1 L homeolog, anticorps PDZK1, anticorps pdzk1.L, anticorps pdzk1, anticorps Pdzk1

Sujet:

Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

Gene: PDZK1

Poids moléculaire: 57kDa

ID gène: 5174

UniProt: Q5T2W1