PLA2G2A anticorps (Internal Region)
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- Antigène Voir toutes PLA2G2A Anticorps
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
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Épitope
- Internal Region
- Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PLA2G2A est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- PLA2G2A Antibody detects endogenous levels of total PLA2G2A.
- Homologie
- Pig,Horse,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human PLA2G2A, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PLA2G2A Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
- Autre désignation
- PLA2G2A (PLA2G2A Produits)
- Synonymes
- anticorps MOM1, anticorps PLA2, anticorps PLA2B, anticorps PLA2L, anticorps PLA2S, anticorps PLAS1, anticorps sPLA2, anticorps EF, anticorps Mom1, anticorps Pla2, anticorps sPla2-IIA, anticorps phospholipase A2 group IIA, anticorps phospholipase A2, group IIA (platelets, synovial fluid), anticorps PLA2G2A, anticorps Pla2g2a
- Sujet
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Description: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Gene: PLA2G2A
- Poids moléculaire
- 16kDa
- ID gène
- 5320
- UniProt
- P14555
- Pathways
- Stem Cell Maintenance, Inositol Metabolic Process
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