POLR3E anticorps (N-Term)

N° du produit ABIN6264350

Détail du produit anti-POLR3E anticorps

Antigène: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR3E est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: POLR3E Antibody detects endogenous levels of total POLR3E.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human POLR3E, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur POLR3E

Antigène: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Autre désignation: POLR3E (POLR3E Produits)

Synonymes: anticorps RPC5, anticorps SIN, anticorps Sin, anticorps MGC78924, anticorps RGD1308086, anticorps wu:fb12d10, anticorps wu:fs42e03, anticorps zgc:55592, anticorps RNA polymerase III subunit E, anticorps polymerase (RNA) III (DNA directed) polypeptide E, anticorps polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog, anticorps polymerase (RNA) III (DNA directed) polypeptide E (80kD), anticorps DNA-directed RNA polymerase III subunit RPC5, anticorps POLR3E, anticorps Polr3e, anticorps polr3e.L, anticorps polr3e, anticorps LOC608689

Sujet:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Gene: POLR3E

Poids moléculaire: 80kDa

ID gène: 55718

UniProt: Q9NVU0