PRDM14 anticorps (N-Term)

N° du produit ABIN6264408

Détail du produit anti-PRDM14 anticorps

Antigène: PRDM14 (PR Domain Containing 14 (PRDM14))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)

Specificité: PRDM14 Antibody detects endogenous levels of total PRDM14.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PRDM14, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:20-1:100, CHIP 1:20-1:100, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PRDM14

Antigène: PRDM14 (PR Domain Containing 14 (PRDM14))

Autre désignation: PRDM14 (PRDM14 Produits)

Synonymes: anticorps PFM11, anticorps PRDM14, anticorps prmd14, anticorps fc16b12, anticorps wu:fc16b12, anticorps PR/SET domain 14, anticorps PR domain containing 14, anticorps PRDM14, anticorps Prdm14, anticorps prdm14

Sujet:

Description: Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'.

Gene: PRDM14

Poids moléculaire: 64kDa

ID gène: 63978

UniProt: Q9GZV8