PREX1 anticorps (Internal Region)

N° du produit ABIN6264416

Détail du produit anti-PREX1 anticorps

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PREX1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: PREX1 Antibody detects endogenous levels of total PREX1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PREX1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PREX1

Antigène: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Autre désignation: PREX1 (PREX1 Produits)

Synonymes: anticorps MGC68772, anticorps P-REX1, anticorps G630042G04, anticorps Setd6, anticorps RGD1306534, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog, anticorps phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1, anticorps phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1, anticorps prex1.L, anticorps PREX1, anticorps prex1, anticorps Prex1

Sujet:

Description: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Gene: PREX1

Poids moléculaire: 186 kDa

ID gène: 57580

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization