RCC1 anticorps (N-Term)
-
- Antigène Voir toutes RCC1 Anticorps
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RCC1 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Specificité
- RCC1 Antibody detects endogenous levels of total RCC1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human RCC1, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product RCC1 Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
-
- Antigène
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- Autre désignation
- RCC1 (RCC1 Produits)
- Synonymes
- anticorps Chc1, anticorps zgc:65796, anticorps zgc:77114, anticorps wu:fj77f08, anticorps rcc1, anticorps chc1-a, anticorps BJ1, anticorps CG10480, anticorps CG18640 (Bj1), anticorps Dmel\\CG10480, anticorps RCC1, anticorps RanGEF, anticorps Rcc1, anticorps dRCC1, anticorps inxs, anticorps sdt, anticorps xrcc1, anticorps chc1-b, anticorps MGC115703, anticorps MGC132085, anticorps CHC1, anticorps RCC1-I, anticorps SNHG3-RCC1, anticorps 4931417M11Rik, anticorps AI326872, anticorps regulator of chromosome condensation 1, anticorps regulator of chromosome condensation 1 L homeolog, anticorps Regulator of chromosome condensation 1, anticorps N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted, anticorps regulator of chromosome condensation 1 S homeolog, anticorps rcc1, anticorps RCC1, anticorps rcc1.L, anticorps Rcc1, anticorps rcc1.S
- Sujet
-
Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).
Gene: RCC1
- Poids moléculaire
- ?45 kDa
- ID gène
- 1104
- UniProt
- P18754
- Pathways
- Chromatin Binding, Protein targeting to Nucleus
-