RGS2 anticorps (Internal Region)

N° du produit ABIN6264723

Détail du produit anti-RGS2 anticorps

Antigène: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: RGS2 Antibody detects endogenous levels of total RGS2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RGS2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RGS2

Antigène: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Autre désignation: RGS2 (RGS2 Produits)

Synonymes: anticorps G0S8, anticorps GOS8, anticorps fa96c08, anticorps wu:fa96c08, anticorps wu:fj08f11, anticorps zgc:91965, anticorps g0s8, anticorps regulator of G protein signaling 2, anticorps regulator of G-protein signaling 2, anticorps regulator of G-protein signaling 2, 24kDa, anticorps regulator of G-protein signaling 2 L homeolog, anticorps RGS2, anticorps Rgs2, anticorps rgs2, anticorps rgs2.L

Sujet:

Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).

Gene: RGS2

Poids moléculaire: 24kDa

ID gène: 5997

UniProt: P41220

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation