RNF5 anticorps (C-Term)

N° du produit ABIN6264790

Détail du produit anti-RNF5 anticorps

Antigène: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF5 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RNF5 Antibody detects endogenous levels of total RNF5.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RNF5, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RNF5

Antigène: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Autre désignation: RNF5 (RNF5 Produits)

Synonymes: anticorps 2410131O05Rik, anticorps AA407576, anticorps NG2, anticorps RING5, anticorps RMA1, anticorps ring finger protein 5, anticorps Rnf5, anticorps RNF5

Sujet:

Description: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.

Gene: RNF5

Poids moléculaire: 20 kDa

ID gène: 6048

UniProt: Q99942