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SENP2 anticorps

SENP2 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264984
  • Antigène Voir toutes SENP2 Anticorps
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Reactivité
    • 38
    • 31
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 47
    • 7
    Lapin
    Clonalité
    • 47
    • 7
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SENP2 est non-conjugé
    Application
    • 44
    • 18
    • 17
    • 13
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    SENP2 Antibody detects endogenous levels of total SENP2
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SENP2
    Isotype
    IgG
    Top Product
    Discover our top product SENP2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000 IF/ICC 1:200-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Autre désignation
    SENP2 (SENP2 Produits)
    Synonymes
    anticorps 2310007L05Rik, anticorps 4930538C18Rik, anticorps AI646780, anticorps AW554757, anticorps Smt3ip2, anticorps SuPr-1, anticorps mKIAA1331, anticorps AXAM2, anticorps SMT3IP2, anticorps Axam, anticorps SUMO/sentrin specific peptidase 2, anticorps SUMO1/sentrin/SMT3 specific peptidase 2, anticorps Sumo1/sentrin/SMT3 specific peptidase 2, anticorps Senp2, anticorps SENP2
    Sujet

    Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

    Gene: SENP2

    Poids moléculaire
    68 kDa
    ID gène
    59343
    UniProt
    Q9HC62
    Pathways
    Chromatin Binding
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