SIAH2 anticorps (C-Term)
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- Antigène Voir toutes SIAH2 Anticorps
- SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIAH2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- SIAH2 Antibody detects endogenous levels of total SIAH2.
- Homologie
- Pig,Bovine,Sheep,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human SIAH2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
- Autre désignation
- SIAH2 (SIAH2 Produits)
- Synonymes
- anticorps hSiah2, anticorps Xsiah-2, anticorps siah2-A, anticorps xsiah2, anticorps AA415433, anticorps Sinh2, anticorps siah E3 ubiquitin protein ligase 2, anticorps siah E3 ubiquitin protein ligase 2 L homeolog, anticorps seven in absentia 2, anticorps SIAH2, anticorps siah2.L, anticorps Siah2
- Sujet
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Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Gene: MEN1
- Poids moléculaire
- 36 kDa
- ID gène
- 6478
- UniProt
- O43255
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