SMYD2A anticorps (Internal Region)
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- Antigène Voir toutes SMYD2A Anticorps
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMYD2A est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- SMYD2 Antibody detects endogenous levels of total SMYD2.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human SMYD2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SMYD2A Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
- Autre désignation
- SMYD2 (SMYD2A Produits)
- Synonymes
- anticorps HSKM-B, anticorps KMT3C, anticorps ZMYND14, anticorps 1110020E07Rik, anticorps 4930402C15, anticorps Zmynd14, anticorps smyd2-a, anticorps im:7146196, anticorps smyd2, anticorps wu:fc02f02, anticorps zgc:110553, anticorps si:dkey-121j17.3, anticorps zgc:136609, anticorps SET and MYND domain containing 2, anticorps SET and MYND domain containing 2 S homeolog, anticorps SET and MYND domain containing 2a, anticorps SET and MYND domain containing 2b, anticorps SMYD2, anticorps Smyd2, anticorps smyd2.S, anticorps smyd2a, anticorps smyd2b
- Sujet
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Description: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
Gene: SMYD2
- Poids moléculaire
- 49 kDa
- ID gène
- 56950
- UniProt
- Q9NRG4
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