SPDYA anticorps (Internal Region)

N° du produit ABIN6265255

Détail du produit anti-SPDYA anticorps

Antigène: SPDYA (Speedy Homolog A (SPDYA))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPDYA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Specificité: SPDYA Antibody detects endogenous levels of total SPDYA.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SPDYA, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SPDYA

Antigène: SPDYA (Speedy Homolog A (SPDYA))

Autre désignation: SPDYA (SPDYA Produits)

Synonymes: anticorps zgc:101624, anticorps 4921517J08Rik, anticorps 4930548B21Rik, anticorps GS4, anticorps MLZ-465, anticorps Spdy1, anticorps RINGO, anticorps SPDY1, anticorps RINGO3, anticorps RINGOA, anticorps SPY1, anticorps Gs4, anticorps Lm23, anticorps Spy1, anticorps speedy homolog A (Xenopus laevis), anticorps speedy/RINGO cell cycle regulator family member A, anticorps speedy/RINGO cell cycle regulator family, member A, anticorps SPDYA, anticorps spdya, anticorps Spdya

Sujet:

Description: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555). Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995). Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962).

Gene: SPDYA

Poids moléculaire: 36kDa

ID gène: 245711

UniProt: Q5MJ70