STAMBP anticorps (C-Term)
-
- Antigène Voir toutes STAMBP Anticorps
- STAMBP (STAM Binding Protein (STAMBP))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp STAMBP est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Specificité
- STAMBP Antibody detects endogenous levels of total STAMBP.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product STAMBP Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
-
- Antigène
- STAMBP (STAM Binding Protein (STAMBP))
- Autre désignation
- STAMBP (STAMBP Produits)
- Synonymes
- anticorps AMSH, anticorps 5330424L14Rik, anticorps 5730422L11Rik, anticorps AW107289, anticorps Amsh, anticorps mKIAA4198, anticorps stambp, anticorps zgc:66147, anticorps STAM binding protein, anticorps Stam binding protein, anticorps STAM binding protein a, anticorps STAMBP, anticorps Stambp, anticorps stambpa
- Sujet
-
Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
Gene: STAMBP
- Poids moléculaire
- 50 kDa
- ID gène
- 10617
- UniProt
- O95630
-