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STAMBP anticorps (C-Term)

STAMBP Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265307
  • Antigène Voir toutes STAMBP Anticorps
    STAMBP (STAM Binding Protein (STAMBP))
    Épitope
    • 15
    • 10
    • 8
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 44
    • 30
    • 19
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 56
    • 4
    Lapin
    Clonalité
    • 57
    • 3
    Polyclonal
    Conjugué
    • 24
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STAMBP est non-conjugé
    Application
    • 35
    • 22
    • 19
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    STAMBP Antibody detects endogenous levels of total STAMBP.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product STAMBP Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    STAMBP (STAM Binding Protein (STAMBP))
    Autre désignation
    STAMBP (STAMBP Produits)
    Synonymes
    anticorps AMSH, anticorps 5330424L14Rik, anticorps 5730422L11Rik, anticorps AW107289, anticorps Amsh, anticorps mKIAA4198, anticorps stambp, anticorps zgc:66147, anticorps STAM binding protein, anticorps Stam binding protein, anticorps STAM binding protein a, anticorps STAMBP, anticorps Stambp, anticorps stambpa
    Sujet

    Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Gene: STAMBP

    Poids moléculaire
    50 kDa
    ID gène
    10617
    UniProt
    O95630
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