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SUPT16H anticorps (C-Term)

SUPT16H Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6267018
  • Antigène Voir toutes SUPT16H Anticorps
    SUPT16H (FACT complex subunit SPT16 (SUPT16H))
    Épitope
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 43
    • 23
    • 14
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris
    Hôte
    • 45
    • 6
    • 1
    Lapin
    Clonalité
    • 46
    • 6
    Polyclonal
    Conjugué
    • 35
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SUPT16H est non-conjugé
    Application
    • 30
    • 23
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    SUPT16H Antibody detects endogenous levels of total SUPT16H.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SUPT16H, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SUPT16H Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    SUPT16H (FACT complex subunit SPT16 (SUPT16H))
    Autre désignation
    SUPT16H (SUPT16H Produits)
    Synonymes
    anticorps CDC68, anticorps FACTP140, anticorps SPT16/CDC68, anticorps CG1828, anticorps DRE4/dSPT16, anticorps Dmel\\CG1828, anticorps SPT16, anticorps Spt16, anticorps dSPT16, anticorps dSpt16, anticorps dspt16, anticorps l(3)62Bg, anticorps l(3)dre4, anticorps spt16, anticorps Cdc68, anticorps Fact140, anticorps Supt16h, anticorps T12H20.3, anticorps T12H20_3, anticorps global transcription factor C, anticorps SSF1, anticorps DDBDRAFT_0204912, anticorps DDBDRAFT_0231753, anticorps DDB_0204912, anticorps DDB_0231753, anticorps DUF140, anticorps SPT16 homolog, facilitates chromatin remodeling subunit, anticorps FACT complex subunit spt16, anticorps FACT complex subunit SPT16, anticorps CG1828 gene product from transcript CG1828-RB, anticorps suppressor of Ty 16, anticorps global transcription factor C, anticorps chromatin-remodeling protein SPT16, anticorps FACT complex component Spt16, anticorps chromatin-remodeling protein, anticorps global regulator of transcription, anticorps FACT (FAcilitates Chromatin Transcription) complex subunit, putative, anticorps SPT16 homolog, facilitates chromatin remodeling subunit S homeolog, anticorps SUPT16H, anticorps AOR_1_1808194, anticorps CC1G_05155, anticorps dre4, anticorps Supt16, anticorps SPT16, anticorps spt16, anticorps CDC68, anticorps Supt16h, anticorps supt16h, anticorps supt16h.S
    Sujet

    Description: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II).

    Gene: SUPT16H

    Poids moléculaire
    119kDa
    ID gène
    11198
    UniProt
    Q9Y5B9
    Pathways
    Chromatin Binding
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