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SYNGAP1 anticorps (C-Term)

SYNGAP1 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265400
  • Antigène Voir toutes SYNGAP1 Anticorps
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 20
    • 15
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 19
    • 2
    Lapin
    Clonalité
    • 18
    • 3
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SYNGAP1 est non-conjugé
    Application
    • 10
    • 7
    • 5
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificité
    SYNGAP1 Antibody detects endogenous levels of total SYNGAP1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SYNGAP1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SYNGAP1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Autre désignation
    SYNGAP1 (SYNGAP1 Produits)
    Synonymes
    anticorps SYNGAP1, anticorps Syngap, anticorps MRD5, anticorps RASA1, anticorps RASA5, anticorps SYNGAP, anticorps Gm1963, anticorps synaptic Ras GTPase activating protein 1, anticorps zinc finger and BTB domain containing 9, anticorps synaptic Ras GTPase activating protein 1 homolog (rat), anticorps SYNGAP1, anticorps ZBTB9, anticorps syngap1, anticorps Syngap1
    Sujet

    Description: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

    Gene: SYNGAP1

    Poids moléculaire
    147 kDa
    ID gène
    8831
    UniProt
    Q96PV0
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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