TCOF1 anticorps (N-Term)

N° du produit ABIN6265504

Détail du produit anti-TCOF1 anticorps

Antigène: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Épitope: N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCOF1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TCOF1 Antibody detects endogenous levels of total TCOF1.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TCOF1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TCOF1

Antigène: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Autre désignation: TCOF1 (TCOF1 Produits)

Synonymes: anticorps TCOF1, anticorps AA408847, anticorps AW209012, anticorps treacle, anticorps MFD1, anticorps TCS1, anticorps treacle ribosome biogenesis factor 1, anticorps Tcof1, anticorps TCOF1

Sujet:

Description: Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:12777385, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).

Gene: TCOF1

Poids moléculaire: 152kDa

ID gène: 6949

UniProt: Q13428