TCTN1 anticorps (N-Term)

N° du produit ABIN6265507

Détail du produit anti-TCTN1 anticorps

Antigène: TCTN1 (Tectonic Family Member 1 (TCTN1))

Épitope: N-Term

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCTN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: TCTN1 Antibody detects endogenous levels of total TCTN1.

Homologie: Pig

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TCTN1

Antigène: TCTN1 (Tectonic Family Member 1 (TCTN1))

Autre désignation: TCTN1 (TCTN1 Produits)

Synonymes: anticorps FLJ21127, anticorps JBTS13, anticorps TECT1, anticorps G730031O11Rik, anticorps Tect1, anticorps RGD1566266, anticorps tectonic family member 1, anticorps tectonic family member 1 L homeolog, anticorps TCTN1, anticorps tctn1.L, anticorps tctn1, anticorps Tctn1

Sujet:

Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

Gene: TCTN1

Poids moléculaire: 55-64kDa

ID gène: 79600

UniProt: Q2MV58

Pathways: Tube Formation