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TCTN1 anticorps (N-Term)

TCTN1 Reactivité: Rat, Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265507
  • Antigène Voir toutes TCTN1 Anticorps
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Épitope
    • 15
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Rat, Humain, Souris
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCTN1 est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    TCTN1 Antibody detects endogenous levels of total TCTN1.
    Homologie
    Pig
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Autre désignation
    TCTN1 (TCTN1 Produits)
    Synonymes
    anticorps FLJ21127, anticorps JBTS13, anticorps TECT1, anticorps G730031O11Rik, anticorps Tect1, anticorps RGD1566266, anticorps tectonic family member 1, anticorps tectonic family member 1 L homeolog, anticorps TCTN1, anticorps tctn1.L, anticorps tctn1, anticorps Tctn1
    Sujet

    Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

    Gene: TCTN1

    Poids moléculaire
    55-64kDa
    ID gène
    79600
    UniProt
    Q2MV58
    Pathways
    Tube Formation
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