TDGF1 anticorps (Internal Region)

N° du produit ABIN6265513

Détail du produit anti-TDGF1 anticorps

Antigène: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDGF1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TDGF1 Antibody detects endogenous levels of total TDGF1.

Homologie: Pig,Bovine,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TDGF1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TDGF1

Antigène: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Autre désignation: TDGF1 (TDGF1 Produits)

Synonymes: anticorps CR, anticorps CRGF, anticorps CRIPTO, anticorps CR1, anticorps cripto, anticorps cb85, anticorps tdgf1, anticorps wu:fe01d04, anticorps zgc:109829, anticorps Cripto-1, anticorps cr1, anticorps cr1a, anticorps frl-1, anticorps frl1, anticorps xcr1, anticorps TDGF1, anticorps tdgf3, anticorps cripto-3, anticorps teratocarcinoma-derived growth factor 1, anticorps teratocarcinoma-derived growth factor 1, member 3 L homeolog, anticorps teratocarcinoma-derived growth factor 1, member 1, anticorps TDGF1, anticorps Tdgf1, anticorps tdgf1, anticorps tdgf1.3.L, anticorps tdgf1.1

Sujet:

Description: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Gene: TDGF1

Poids moléculaire: 21kDa

ID gène: 6997

UniProt: P13385

Pathways: EGFR Signaling Pathway