TINF2 anticorps (Internal Region)

N° du produit ABIN6265586

Détail du produit anti-TINF2 anticorps

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TINF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TINF2 Antibody detects endogenous levels of total TINF2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TINF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TINF2

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Autre désignation: TINF2 (TIN2 Produits)

Synonymes: anticorps DKCA3, anticorps TIN2, anticorps AW552114, anticorps D14Wsu146e, anticorps Tin2, anticorps TERF1 interacting nuclear factor 2, anticorps Terf1 (TRF1)-interacting nuclear factor 2, anticorps TINF2, anticorps Tinf2

Sujet:

Description: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Gene: TINF2

Poids moléculaire: 53kDa

ID gène: 26277

UniProt: Q9BSI4

Pathways: Cycle Cellulaire, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process