TMPRSS2 anticorps (Internal Region)
-
- Antigène Voir toutes TMPRSS2 Anticorps
- TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TMPRSS2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- TMPRSS2 Antibody detects endogenous levels of total TMPRSS2.
- Homologie
- Pig,Bovine,Horse,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human TMPRSS2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TMPRSS2 Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
-
- Antigène
- TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
- Autre désignation
- TMPRSS2 (TMPRSS2 Produits)
- Synonymes
- anticorps PP9284, anticorps PRSS10, anticorps D16Ertd61e, anticorps transmembrane protease serine 2-like, anticorps transmembrane protease, serine 2, anticorps LOC100739411, anticorps TMPRSS2, anticorps Tmprss2
- Sujet
-
Description: Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9), involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.
Gene: TMPRSS2
- Poids moléculaire
- 54 kDa
- ID gène
- 7113
- UniProt
- O15393
- Pathways
- SARS-CoV-2 Protein Interactome
-