TRAP1 anticorps (Internal Region)

N° du produit ABIN6265714

Détail du produit anti-TRAP1 anticorps

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TRAP1 Antibody detects endogenous levels of total TRAP1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TRAP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TRAP1

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Autre désignation: TRAP1 (TRAP1 Produits)

Synonymes: anticorps HSP 75, anticorps HSP75, anticorps HSP90L, anticorps TRAP-1, anticorps 2410002K23Rik, anticorps fc85a11, anticorps wu:fc85a11, anticorps TNF receptor associated protein 1, anticorps TNF receptor-associated protein 1, anticorps TRAP1, anticorps Trap1, anticorps trap1

Sujet:

Description: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Gene: TRAP1

Poids moléculaire: 80kDa

ID gène: 10131

UniProt: Q12931