TSG101 anticorps
-
- Antigène Voir toutes TSG101 Anticorps
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
-
Reactivité
- Humain, Singe
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TSG101 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- TSG101 Antibody detects endogenous levels of total TSG101
- Réactivité croisée
- Humain, Singe
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human TSG101
- Isotype
- IgG
- Top Product
- Discover our top product TSG101 Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
-
- Antigène
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Autre désignation
- TSG101 (TSG101 Produits)
- Sujet
-
Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).
Gene: TSG101
- Poids moléculaire
- 45 kDa
- ID gène
- 7251
- UniProt
- Q99816
-