TSHZ3 anticorps (Internal Region)
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- Antigène Voir toutes TSHZ3 Anticorps
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TSHZ3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- TSH3 Antibody detects endogenous levels of total TSH3.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human TSH3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TSHZ3 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
- Autre désignation
- TSHZ3 (TSHZ3 Produits)
- Synonymes
- anticorps ZNF537, anticorps A630038G13Rik, anticorps Tsh3, anticorps Zfp537, anticorps mKIAA1474, anticorps teashirt3, anticorps TSH3, anticorps teashirt zinc finger homeobox 3, anticorps teashirt zinc finger family member 3, anticorps TSHZ3, anticorps Tshz3
- Sujet
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Description: Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity).
Gene: TSHZ3
- Poids moléculaire
- 119 kDa
- ID gène
- 57616
- UniProt
- Q63HK5
- Pathways
- Regulation of Muscle Cell Differentiation
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