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NPRL2 anticorps (C-Term)

NPRL2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265808
  • Antigène Voir toutes NPRL2 Anticorps
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Épitope
    • 15
    • 9
    • 8
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 53
    • 31
    • 18
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 50
    • 2
    • 1
    Lapin
    Clonalité
    • 53
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NPRL2 est non-conjugé
    Application
    • 44
    • 21
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    TUSC4 Antibody detects endogenous levels of total TUSC4.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human TUSC4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NPRL2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Autre désignation
    NPRL2 (NPRL2 Produits)
    Synonymes
    anticorps 2810446G01Rik, anticorps G21, anticorps NPR2L, anticorps Tusc4, anticorps npr2, anticorps npr2l, anticorps tusc4, anticorps NPR2, anticorps TUSC4, anticorps im:6900399, anticorps zgc:153630, anticorps nitrogen permease regulator-like 2, anticorps NPR2 like, GATOR1 complex subunit S homeolog, anticorps NPR2 like, GATOR1 complex subunit, anticorps NPR2-like, GATOR1 complex subunit, anticorps Nprl2, anticorps nprl2.S, anticorps NPRL2, anticorps nprl2
    Sujet

    Description: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

    Gene: NPRL2

    Poids moléculaire
    44 kDa
    ID gène
    10641
    UniProt
    Q8WTW4
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