UBA52 anticorps (Internal Region)
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- Antigène Voir toutes UBA52 Anticorps
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
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Épitope
- Internal Region
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBA52 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- UBA52 Antibody detects endogenous levels of total UBA52.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human UBA52, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product UBA52 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200, WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
- Autre désignation
- UBA52 (UBA52 Produits)
- Synonymes
- anticorps CEP52, anticorps HUBCEP52, anticorps L40, anticorps RPL40, anticorps D8Ertd21e, anticorps Gm1863, anticorps Rps27a, anticorps Ubb, anticorps Ubc, anticorps UBCEP2, anticorps UB-RPL40, anticorps MGC80109, anticorps cep52, anticorps hubcep52, anticorps rpl40, anticorps RPS27A, anticorps UBB, anticorps UBC, anticorps wu:fa91f08, anticorps zgc:123344, anticorps UBA52, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog, anticorps UBA52, anticorps Uba52, anticorps uba52.L, anticorps uba52
- Sujet
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Description: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Gene: UBA52
- Poids moléculaire
- 8kDa
- ID gène
- 7311
- UniProt
- P62987
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
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