UNC13D anticorps (C-Term)
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- Antigène Voir toutes UNC13D Anticorps
- UNC13D (Unc-13 Homolog D (UNC13D))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UNC13D est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- UNC13D Antibody detects endogenous levels of total UNC13D.
- Homologie
- Pig,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human UNC13D, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product UNC13D Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- UNC13D (Unc-13 Homolog D (UNC13D))
- Autre désignation
- UNC13D (UNC13D Produits)
- Synonymes
- anticorps FHL3, anticorps HLH3, anticorps HPLH3, anticorps Munc13-4, anticorps UNC13D, anticorps 2610108D09Rik, anticorps Jinx, anticorps mFLJ00067, anticorps Unc13h4, anticorps BIGH3, anticorps CDB1, anticorps CDG2, anticorps CDGG1, anticorps CSD, anticorps CSD1, anticorps CSD2, anticorps CSD3, anticorps EBMD, anticorps LCD1, anticorps unc-13 homolog D, anticorps unc-13 homolog D (C. elegans), anticorps transforming growth factor beta induced, anticorps UNC13D, anticorps Unc13d, anticorps TGFBI, anticorps unc13d, anticorps un13d
- Sujet
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Description: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells.
Gene: UNC13D
- Poids moléculaire
- 123 kDa
- ID gène
- 201294
- UniProt
- Q70J99
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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