USP51 anticorps

N° du produit ABIN6265932

Détail du produit anti-USP51 anticorps

Antigène: USP51 (Ubiquitin Specific Peptidase 51 (USP51))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP51 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: USP51 Antibody detects endogenous levels of total USP51

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human USP51

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur USP51

Antigène: USP51 (Ubiquitin Specific Peptidase 51 (USP51))

Autre désignation: USP51 (USP51 Produits)

Synonymes: anticorps AV136873, anticorps ubiquitin specific peptidase 51, anticorps ubiquitin specific protease 51, anticorps USP51, anticorps Usp51

Sujet:

Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).

Gene: USP51

Poids moléculaire: 80 kDa

ID gène: 158880

UniProt: Q70EK9