WNK3 anticorps (C-Term)
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- Antigène Voir toutes WNK3 Anticorps
- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WNK3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- WNK3 Antibody detects endogenous levels of total WNK3.
- Homologie
- Pig,Horse,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human WNK3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product WNK3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))
- Autre désignation
- WNK3 (WNK3 Produits)
- Synonymes
- anticorps fc63h12, anticorps PRKWNK3, anticorps Prkwnk3, anticorps Wnk3-ps, anticorps RGD1563131, anticorps wu:fc63h12, anticorps WNK lysine deficient protein kinase 3, anticorps wu:fc63h12, anticorps LOC100363278, anticorps WNK3, anticorps Wnk3
- Sujet
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Description: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca2+ influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.
Gene: WNK3
- Poids moléculaire
- 198kDa
- ID gène
- 65267
- UniProt
- Q9BYP7
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