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YTHDF1 anticorps (N-Term)

YTHDF1 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6266080
  • Antigène Tous les produits YTHDF1
    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
    Épitope
    • 4
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 20
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 20
    Lapin
    Clonalité
    • 19
    • 1
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp YTHDF1 est non-conjugé
    Application
    • 11
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    YTHDF1 Antibody detects endogenous levels of total YTHDF1.
    Homologie
    Pig,Bovine,Horse,Sheep,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human YTHDF1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
    Autre désignation
    YTHDF1 (YTHDF1 Produits)
    Synonymes
    anticorps fb49c02, anticorps zgc:55657, anticorps wu:fb49c02, anticorps wu:fi19h06, anticorps wu:fj87f09, anticorps wu:fp06c11, anticorps MGC75606, anticorps MGC68505, anticorps 2210410K23Rik, anticorps 8030473O16, anticorps C20orf21, anticorps YTH N(6)-methyladenosine RNA binding protein 1, anticorps YTH N(6)-methyladenosine RNA binding protein 1 L homeolog, anticorps YTH N6-methyladenosine RNA binding protein 1, anticorps YTH domain family 1, anticorps ythdf1, anticorps ythdf1.L, anticorps YTHDF1, anticorps Ythdf1
    Sujet

    Description: Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).

    Gene: YTHDF1

    Poids moléculaire
    61kDa
    ID gène
    54915
    UniProt
    Q9BYJ9
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