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PARD6A anticorps (N-Term)

PARD6A Reactivité: Humain, Souris, Rat ELISA, WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6266264
  • Antigène Voir toutes PARD6A Anticorps
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Épitope
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 24
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 24
    • 2
    • 1
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARD6A est non-conjugé
    Application
    • 15
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    PARD6A Antibody detects endogenous levels of total PARD6A.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PARD6A, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PARD6A Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Autre désignation
    PARD6A (PARD6A Produits)
    Synonymes
    anticorps PARD6A, anticorps 0710008C04Rik, anticorps 2610010A15Rik, anticorps PAR6alpha, anticorps Par-6, anticorps Par6, anticorps Par6c, anticorps TAX40, anticorps Tip-40, anticorps Par-6a, anticorps Par6a, anticorps PAR-6A, anticorps PAR6, anticorps PAR6C, anticorps TIP-40, anticorps par-6 partitioning defective 6 homolog alpha (C. elegans), anticorps par-6 family cell polarity regulator alpha, anticorps Partitioning defective protein 6, anticorps PARD6A, anticorps Pard6a, anticorps par-6
    Sujet

    Description: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10873802). Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (PubMed:20719959).

    Gene: PARD6A

    Poids moléculaire
    37kDa
    ID gène
    50855
    UniProt
    Q9NPB6
    Pathways
    Cell-Cell Junction Organization
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